One of the main tasks of ecological parasitology at the present stage is to establish patterns of spread of invasive diseases of animals in the environment through a thorough epidemiological examination, as well as to determine the main directions and factors of spread of parasites in Ukraine. Among the many pathogens, endoparasites play a major role in a number of diseases in rabbits with increased morbidity and mortality. In the body of both wild and domestic rabbits several species of parasites that form a parasitocenosis can be localized. The latter have a pathogenic effect on organs and tissues, leading to reduced weight gain, premature slaughter and even mortality. The prevalence of endoparasitoses was studied in weaned rabbits 60 days of age, 120 days of age at fattening, 180 days of age – mating age and adults of 320 days of age to determine the extensiveness and intensity of the dominant invasion. A total of 720 head was studied, 180 animals from each age group. Three species of nematodes were recorded in the rabbits: Trichostrongylus retortaeformis (Zeder, 1800), Nematodirus leporis (Ransom, 1907) and Passalurus ambiguus (Rudolphi, 1819); the cestode Taenia pisiformis (Bloch, 1780); three species of Emeria: Eimeria stiedae (Lindermann, 1865), which parasitizes in the bile ducts of the liver and gallbladder, E. magna (Perard, 1925) and E. media (Kessel, 1929) – in the epithelial cells of the intestine. The prevalence of the infestation depends on the age of the animals. According to the data obtained, eimeriosis was one of the main parasitic diseases of the rabbits. Dominant invasions of Eimeria in the intestines of 60-day-old rabbits were found in the studied animals, their extensiveness reached 19.4%, while the spread of hepatic Eimeria was registered in 13.3% of the examined rabbits. The total infestation of weaned rabbits with helminths was 22.2%, in rabbits for fattening – 26.7%, and in rabbits of mating age and adults – 20.0% and 20.6%, respectively. Global climate change will change the distribution and dynamics of soil-borne helminthiases, but host immunity may also affect host-parasite interactions. Subsequent studies will be aimed at elucidating the effect of mono and mixed invasions on the body of rabbits. Updated data on helminthiasis will expand the screening strategy to maintain rabbit health and reduce economic losses.

Control of feed contamination by micromycetes and bacteria at all stages of their preparation, storage, and feeding of farm animals is an acute issue of feed safety and one of the principal measures that create an opportunity to prevent their negative impact on animal health. Therefore, the study aimed to investigate the state of metabolic processes in cattle of different physiological groups under the influence of biotic feed contaminants. The material for the research was grain fodder and coarse grinding grain of local production, roughage used on the farm. Veterinary and sanitary condition of grain products was established based on organoleptic, toxico-biological and microbiological studies. To determine the indicators of the state of metabolic processes, 3 groups of cows (n = 5–7) with different physiological conditions were formed: group I — non-pregnant cows, group II — pregnant animals with normal pregnancy, group III — cows after miscarriage. Biochemical parameters (level of total protein, albumin, globulins, vitamins A and E) in blood serum samples were determined spectrophotometrically by conventional methods. The study of the content of inorganic elements in the aggregate samples of bovine sera was performed using an X-ray spectrometer ‘Spectroscan MAX’. Laboratory studies have proven the presence of biotic contaminants in the feed base of the experimental farm. Exceedance of maximum permissible levels of feed contamination (max 16.50×104 CFU/g when MPL 5.0×104 CFU/g) by toxin-forming micromycetes (due to the genera Fusarium, Aspergillus, Penicillium, Mucor, and Rhizopus; a total of 24 isolates of microscopic fungi were isolated, which showed high toxicity in 11.3% and weak — in 20.1% of samples) and total bacterial contamination (max 18.7×105 CFU/g when MPL 5.0×105 CFU/g), in the structure of which coliform bacteria and Salmonella enterica were isolated. In cattle that consumed feed with an excess of biotic contaminants, disorders of the digestive tract (diarrhea) and reproductive capacity (abortions in the first half of pregnancy) were observed and metabolic disorders were found in cattle: increased Iron (on average 1.5 times) and Bromine (on average 1.6 times) levels, a decrease in the concentration of vitamin A (by 17.4–39.8%), and vitamin E (by 10.0–12.5%), most pronounced in cows after abortion and pregnant cows, respectively, Manganese (on average by 12.5%) and Selenium (by 30.7%)

During the migration period of Cysticercus pisiformis, the largest changes in the morphological parameters of rabbit blood occur on the 25th and 35th day and register hemoglobinemia (78.97 ± 1.21 g / l and 80.22 ± 1.01 g / l) (р˂0.001)), erythropenia (3.76 ± 0.21 T / l and 3.98 ± 0.11 T / l (p˂0.001)) and an increase in white blood cells by 32.1% and 29.1%. Eosinophilia (6.24 ± 0.31 and 5.02 ± 0.12% (p˂0.01)), lymphopenia, monocytosis and an increase in rod-shaped neutrophils by 61.4% and 47.3% were registered in the leukoformula. An increase in the leukocyte intoxication index by 43.9% and 51.5% indicates a significant inflammatory process during the migration of C. pisiformis.

The article presents information on the results of monitoring regarding paramyxovirus diseases of fancy pigeons in the South Ukraine. Seropositivity to the PMV-1 virus was stated in the blood of fancy pigeons and their young (average antibody titer 3.2 log2 and 9.7 log2, respectively), while clinical signs of the disease were not ob-served in all birds, the infection being manifested in a subclinical form.