The beginning of the development of noninvasive optical blood glucose monitoring dates back to 30 years ago. Since then, dozens of noninvasive blood glucose monitoring methods have emerged. Optical methods for measurement of blood glucose concentration are the most promising.Safety for the patient is most important advantage of these methods. The possibility of development of a non invasive glucometer based on optical monitoring methods was reported in the literature. The causes for unsuccessful attempts in the development of noninvasive glucometer are: individual specificity of physiology of each patient, difficult interpretation of test results, necessary optimal calibration of glucometer, etc.The glucometer error is determined in the DIN EN ISO 15197:2003 standard. At glucose concentration <75 mg/dl, 95% test results should fall within the error range ±15 mg/dl. At glucose concentration >75 mg/dl, the same fraction of test results should fall within the error range ±20 mg/dl [1].The goal of this work was to review optical methods for noninvasive blood glucose monitoring and their effi ciency and capacity.
The WAK that we developed can eliminate metabolites from spent dialysis fluid with mass rates that are sufficient to maintain stable, physiologically normal metabolite concentrations in patients' blood.
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