The rapid development of new learning algorithms increases the need for improved accuracy estimation methods. Moreover, methods allowing the comparison of several different learning algorithms are important for the performance evaluation of new ones. In this paper we propose new accuracy estimation methods which are extensions of the k-fold cross-validation method. The methods proposed construct cross-validation folds deterministically instead of using the random sampling approach. The deterministic construction of folds is performed using unsupervised stratification by exploiting the distribution of instances in the instance space. Our methods are based either on the one-center approach or on clustering procedures. These methods attempt to construct more representative folds, therefore reducing the bias of the resulting estimator. At the same time, our methods allow direct comparisons between the performance of learning algorithms in different experiments, since no randomness is present. A simulation experiment examining the performance of the proposed methods is reported, depicting their behavior in a variety of situations. The new methods reduce mainly the bias of the estimator.

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A geoeral purpose learoing system for Electrocardiogram (ECG) Diagnosis Expert Systems (DESs) is preseoted io this paper, The maio fuoctions of the proposed system are the following a) It reads the Koowledge &se (KB) of the DES and wostructs the appropriate Database (DB) scheme. b) It interacts with the user, usually a physiciao, io order to m r d his opioion 00 the concluded diagnosis and store it io the DB c) It processes the DB io order to update the KB of the DES The proposed system is frieodly and easy to use, add it upgrades the role of the user, eowuragiog the physiciaos to use ECG diagoosis systems Pioall' it supports the process of wllectiog aod recordiog the experieoce of the expert