The polar bear Ursus maritimus is a circumpolar species classified as vulnerable and included in the IUCN Red List. It is considered to be practically free of helminth parasites with the only species reported being Trichinella spiralis s. l. Samples of feces were collected on Chukotka coast, Wrangel Island and on ice floes in the Kara, Laptev and Chukchi seas in 2013-2015 in different seasons of the year. Coprological diagnostics was carried out using the standard flotation and sedimentation methods. In the samples collected in the snow-free period, a single sample (3.7%) was found to contain eggs of the nematode Toxascaris sp. In three out of 9 samples collected in the winter, eggs of a cestode Diphyllobothrium sp., of unidentified trematodes (presumably Heterophyidae) and of the strongylid nematode Uncinaria stenocephala were found as well as the first stage nematode larvae tentatively identified as Crenosoma sp. Viable Trichinella nativa larvae were recovered from the muscles of a female animal from north of Yakutia.
Background. The Republic of Sakha (Yakutia) is an endemic region for chronic hepatitis D, where the detection rate of antibodies to the delta virus is 35% [3]. The urgency of the problem of HDV infection is also determined by its aggressive and rapidly progressive course. In 2019, Bulevirtide, a drug for the treatment of chronic delta hepatitis, was registered in Russia. Three randomized trials showed a high rate of virological, biochemical response, as well as good tolerability and safety. Objective – to evaluate the efficacy and safety of Bulevirtide in the treatment of chronic HDV infection. Material and methods. A clinical case of a patient L. suffering from a chronic form of HDV infection receiving antiviral therapy is presented. Results. Bulevirtide demonstrated high efficacy, as evidenced by the development of a virological response during the first 14 weeks of therapy and a decrease in HDV RNA to an undetectable level within 29. Conclusions. It is necessary to widely introduce Bulevirtide for the treatment of patients with chronic delta hepatitis due to its high efficacy and safety.
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