Abstract. Urban mobility pattern studies are one of the interesting issues in GIScience which provide appropriate means for urban transportation planning and management. Mobility across the city has a direct relation with the land-use pattern. This paper investigates the spatio-temporal effect of the land-use mix at street level on urban movement. Taxi pick up and drop-off data in Manhattan was chosen as the sample data in this study. Trips are classified into two parts (weekdays and weekends trips) and then the correlation between mixed land-use and number of trips occurred in different time windows in each street segment, is calculated. Results indicate positive impact and moderate correlation between mixed land-use and number of trips. In streets with high Entropy, homogeneous distribution of the number of trips at each time window for the weekend and non-homogeneous trip distribution for employment and commercial and residential areas for weekday trips was observed. Also, in streets with low Entropy, non-homogeneous trip distribution at different time windows for both weekday and weekend were observed upon to dominant land-use.