Diabetic ketoacidosis (DKA) is a life-threatening acute metabolic complication occurring in patients with diabetes, especially in patients with type 1 diabetes (T1D), due to an insulin deficiency. Moderate hypertriglyceridemia is commonly observed in DKA but severe hypertriglyceridemia with a triglyceride level exceeding 10g/L is very rarely reported. We report a case of a 14-year-old boy who had type 1 diabetes for 4 years treated with insulin therapy, also having adrenal insufficiency treated with hydrocortisone who presented with ketoacidosis and excruciating abdominal pain. Investigations revealed hypertriglyceridemia at 64g/L, lipasemia at 1000 U/L, and stage E pancreatitis on abdominal CT. The patient was treated with intravenous insulin, rehydration, and fenofibrate with good clinical and biological evolution. Severe hypertriglyceridemia causing pancreatitis in type 1 diabetes mellitus is a rare but very serious complication of DKA in children.
The desire and feasibility of fasting during Ramadan are sensitive issues for diabetic Muslims. The aim of this study was to describe the behavior of patients with type 2 diabetes towards fasting. A prospective longitudinal study was conducted including 100 patients with type 2 diabetes. Data collection was carried out using an anonymous questionnaire administrated by the attending physician during two visits before and after Ramadan. A total of seventy-nine of the hundred enrolled patients fasted, and 62% of uncontrolled patients fasted against medical advice. The reasons given by patients to justify their behavior referred to socio-cultural imperatives. Most of our patients practice Ramadan fasting under the pressure of sociocultural habits, despite their doctors' disapproval. This fact highlights the difficulties to manage these patients.
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