N Howden scite author profile

Objective-To determine the impact of hormones on the biomechanical properties of the vagina and its supportive tissues following surgical menopause in young vs middle aged rats. Results-OVX induced a rapid decline in the biomechanical properties of pelvic tissues in young but not middle aged rats. Supplementation with E2, E2 + P4, or CMT-8 restored tissues of young rats to control levels with no effect on middle aged tissues. Parity did not impact tissue behavior. Methods-Long-EvansConclusions-OVX has a differential effect on the tissues of young vs middle aged rats.

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N Howden

Risk Factors for Anal Sphincter Tear During Vaginal Delivery

A rat model to study the structural properties of the vagina and its supportive tissues

Hormones restore biomechanical properties of the vagina and supportive tissues after surgical menopause in young rats

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