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Bacillus cereras has been found to be an excellent assay organism in the study of the toxin isolated from rayless goldenrod. Two compounds which inhibit the growth of Bacillus cereus have been isolated from the crude toxin. One of these, dehydrotremetone (2-isopropenyl-5-acetylbenzofuran) recently has been reported to occur in white snakeroot, a poisonous plant that produces symptoms in higher animals similar to those produced by rayless goldenrod. The second, more abundant and more toxic compound, toxol, has not been reported previously. Toxol is shown to be optically active 2-isopropenyl-3-hydroxy-5acetyi-2,3-dihydrobenzofuran.(1) This investigation was generously suppurto*d by tin* National Institutes of Health through research grant RG-8346.(2) To whom inquiries should be sent.(3)

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