In this study, we sought to assess the level of cognitive functioning in patients with comorbid alcohol dependence and affective disorder, as well as to compare the detected changes with the indicators of cognitive tests in patients suffering only from alcoholism or affective disorder. It is suggested that patients with comorbidity may have a more severe cognitive deficit than patients with a single diagnosis.Materials and methods. We examined 100 patients aged 30–50 years before treatment: 30 patients with affective disorders, 40 patients with alcohol dependence and 30 patients with comorbid alcohol dependence and affective disorder. As a control group, 30 mentally and somatically healthy individuals were examined. The level of cognitive functioning was assessed using computer tests Go/No-go, Corsi and Stroop.Results. Statistically significantly lower indicators of cognitive functioning were found in patients with comorbid alcohol dependence and affective disorder in comparison with all the studied groups.Conclusion. The data obtained in the study indicate that the presence of comorbidity of alcohol dependence and affective disorder in patients leads to a significant deterioration in cognitive functions: Executive control, working memory, attention and cognitive flexibility compared to healthy individuals, as well as patients suffering only from alcohol dependence or affective disorder.

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