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Tecomaria Capensis (family: Bignoniaceae) also known as Cape-honeysuckle. The present work aims at evaluating the anti inflammatory activity of Tecomaria Capensis by HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti inflammatory activity. The anti inflammatory activity of the crude Ethyl Acetate extract (EAE), Ethanol extract (EE), Water extract (WE) of leaves part of Tecomaria Capensis were compared to that of the standard drug diclofenac. The percentage protection of lysis for Standard Diclofenac100 µg is 27.203%,Standard Diclofenac 200 µg is 38.972%,Ethyl acetate extract 100µg is 21.985%, Ethyl acetate extract 200µgis 31.765%, Ethanolic extract 100µg is 33.221%, Ethanolic extract 200µgis 41.447%, Aqueous extract 100 µg is 13.25%, Aqueous extract 200µgis 21.112%. The ethanolic extract of Tecomaria capensishas significant anti inflammatory activity in comparison to aqueous extract and ethyl acetate extract of the same plant and with standard drug diclofenac.

Aim: To study the health and socioeconomic impact of the COVID-19 pandemic and to assess the barriers to self-management of diabetes during the lockdown, in rural South India. Materials and Methods: Details of demographic, social, economic, migration and health status were collected using a structured questionnaire from participants aged ≥18 years belonging to the 21 villages of Chengalpattu and Kancheepuram districts of Tamil Nadu state in south India as part of the Telemedicine pRoject for screENing Diabetes and its complications in rural Tamil Nadu (TREND) study. From the 11,249 TREND participants, a random list of 25% (n = 2812) was system-generated using random numbers and 2812 participants were contacted for the study, of whom 2511 individuals participated. Telephonic interviews were conducted during the lockdown from June to August 2020. Further, qualitative interviews(Focus group discussions) were conducted among 27 individuals with diabetes between September and December 2020. Data were analyzed using thematic analysis. Results: The mean age of the study population was 43 ± 14 years and 50.4% were women. Diabetes was present in 14.7%, hypertension in 31.9%, generalized and abdominal obesity in 33.3% and 46.5% respectively. When the lockdown was implemented in March 2020, 37% had migrated from urban to rural areas. Lack of daily wage jobs (68%), price of essential commodities (41.7%), social distancing/curfew (34.8%), mental fatigue/depression (14.7%), and loss of job (7.1%) were some reasons stated for their adverse social and financial circumstances. People with diabetes stated that they had to avoid or cut down their regular hospital visits due to travel restrictions. Many of the patients took the same medications for almost a year. Conclusion: Unemployment, poor mental health, and reduced household income were the most significant negative impacts faced by rural residents during the lockdown due to COVID-19. People with diabetes experienced disruptions in diabetes management due to the pandemic.