The interaction of motor and cognitive brain systems while performing the tasks of processing information of different modality and complexity is an important component of the brain’s integrative activity, which provides the individual adaptation of a person to changing environmental conditions. 116 individuals participated in the research; there were right-handed children aged 7–8, adolescents aged 11–12 and 15–16, and young men aged 19–20 among them. The investigated individuals performed a cognitive task, which included determining the modalities of a signal, the shape of a figure, the meaning of a word, and the fast and error-free reaction of differentiation with left (goL) or right (goR) hand or inhibition of motor action (nogo). The motor task involved a quick reaction to signals of different modality in the go/go/go mode. The results show that in the ontogenesis, the interaction of motor and cognitive brain systems gradually increases during processing of information of different modality and complexity by children, adolescents and young people. Closer functional interaction of motor and cognitive brain systems according to the indicators of speed and success of performing both tasks was found to be greater in the young men aged 19–20 and the adolescents aged 15–16 and 11–12 than in the children aged 7–8. The investigated individuals with the high-speed level of performing cognitive tasks were characterized with reliably higher indicators of motor reactions. Correlation analysis confirmed the statistically significant relationship between the speed characteristics of the motor and cognitive functional systems of the brain. The age dynamics of functional interaction between the motor and cognitive systems, as well as the speed and success of performing tasks depended on the mode selection of information processing. The success and speed of performing different variants of motor tasks in the go/go/go mode were higher in all age groups than in the conditions of the combined motor and cognitive tasks while differentiating goL/nogo/goR. The functional interaction of motor and cognitive brain systems in children, adolescents and young men while processing information increased gradually and depended on the modality of signals. The speed and success of results of performing motor and cognitive tasks were higher than for imaginative signals, and lower than for verbal ones for all age groups. Left-brain dominance of functional asymmetry was found for the cognitive systems. The number of mistakes on words was always less and the reaction speed was higher for the right hand than for the left one in the goL/nogo/goR mode. Asymmetry was weaker in the children aged 7–8 for the combined tasks using imaginative stimuli, and statistically significant in the groups of adolescents aged 11–12 and young men aged 15–16 and 19–20 for verbal signals presented in the goL/nogo/goR mode. The research results and methods can be used for the prognostic estimate of human activity in the conditions of complex information loads and neurodegenerative diseases.

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Journal of Cellular Neuroscience and Oxidative Stress is an online journal that publishes original research articles, reviews and short reviews on the molecular basis of biophysical, physiological and pharmacological processes that regulate cellular function, and the control or alteration of these processes by the action of receptors, neurotransmitters, second messengers, cation, anions, drugs or disease. Areas of particular interest are four topics. They are; A-Ion Channels (Na + -K + Channels, Clchannels, Ca 2+ channels, ADP-Ribose and metabolism of NAD + , Patch-Clamp applications) B-Oxidative Stress (Antioxidant vitamins, antioxidant enzymes, metabolism of nitric oxide, oxidative stress, biophysics, biochemistry and physiology of free oxygen radicals) C-Interaction Between Oxidative Stress and Ion Channels in Neuroscience (Effects of the oxidative stress on the activation of the voltage sensitive cation channels, effect of ADP-Ribose and NAD + on activation of the cation channels which are sensitive to voltage, effect of the oxidative stress on activation of the TRP channels in neurodegenerative diseases such Parkinson's and Alzheimer's diseases) D-Gene and Oxidative Stress (Gene abnormalities. Interaction between gene and free radicals. Gene anomalies and iron. Role of radiation and cancer on gene polymorphism)

Анотація. У статі розглядається питання про застосування комплексного підходу до моделювання ігрової підготовленості футболістів високої кваліфікації. Отримані дані нейродинамічних, біоенергетичних властивостей, показників фізичної та техніко-тактичної підготовленості та розроблені модельні характеристики досліджуваних властивостей у футболістівпрофесіоналів. Між нейродинамічними, біоенергетичними властивостями, показниками фізичної і техніко-тактичної підготовленості та оцінками успішності ігрової діяльності виявлені значущі кореляційні зв'язки. На основі експериментальних даних розроблено протокол комплексного моделювання підготовленості футболістів високої кваліфікації. Обґрунтовано можливості використання нейродинамічних, біоенергетичних властивостей, показників фізичної та техніко-тактичної підготовленості для комплексної оцінки і прогнозування успішності ігрової діяльності футболістів. Ключові слова: Моделювання, нейродинамічні, біоенергетичні властивості, фізична, техніко-тактична підготовка, оцінка успішності ігрової діяльності.

Introduction. It is known that there are typological features among healthy young people according to the level of autonomic tone. Accordingly, there are groups of sympatho-, normo- and vagotonics. Work has been carried out to study the influence of the initial level of autonomic tone on thereactions of the cardiovascular system in respiratory hypocapnia, pulsed ophthalmic photostimulation, in different phases of the biological cycle for women. However, there is no work on the analysis of changes in the wave structure of heart rate depending on the initial level of autonomic tone. Purpose. The aim was to determine the features of the wave structure of the heart rhythm during orthoprobe for healthy young men with different levels of tone of the autonomic nervous system at rest. Methods. Measurements were performed in conditions close to the main exchange. 117 healthy young men aged 18-23 years were examined in compliance with the requirements of bioethics. Three main spectral components were analyzed in the tRR spectrum: HF (0.15-0.4 Hz) LF (0.04-0.15Hz); VLF (0-0.04 Hz); TP (0-0.4 Hz). The amplitude of the largest peak of the tRR spectrogram in the frequency range 0.04-0.15 Hz (aLF) and its frequency (tLF) were calculated. Normalized median spectrograms of tRR oscillations were constructed.Results.A significant decrease in HF was observed in individuals of all three groups during orthoprobe. The median reactivity of reactivity was -67.3%, -77.5%, -77.9% for groups I, II and III, respectively. There were no differences between the groups due to the reactivity of this indicator. The reactivity of LF to changes in body position for sympathotonics was significantly different.The frequency of the maximum peak of the spectrogram in the range of low often resting heart rate did not differ between groups. This indicator probably decreased during orthoprobe in groups IIand III. It was found that the wave has two peaks in the vertical position in persons with different baseline levels of autonomic tone for vagotonics and normotonics in the frequency range from 0.04 to0.15 Hz. Originality. Differences in the reactivity of heart rate waves to orthoprobe for healthy young men with different baseline levels of autonomic tone were detected for the first time. Conclusions. The greatest differences in changes in the wave structure of the heart rhythm during orthoprobe for persons with different baseline levels of autonomic tone are manifested in therange of low heart rate. Spectrum reduction reactions in this range were predominant for sympathotonics. The reactions of increasing LF and the amplitude of the maximum peak of the spectrogram were predominant for normo- and parasympathotonics. It was found that the wave has two peaks in the vertical position in persons with different baseline levels of autonomic tone for vagotonics and normotonics in the frequency range from 0.04 to 0.15 Hz. Sympathotonics have one wave of orthopedic reactivity with maxima at 0.09 Hz in the low heart rate range. Normotonics have two waves of reactivity per orthoprobe with frequencies of 0.08Hz and 0.11 Hz. Parasympathotonics also have two waves with frequencies of 0.07 Hz and 0.09Hz. Prospects for further research include elucidation of the mechanisms of tRR wave formation depending on the level of vegetative tone under different conditions. Key words: wave structure of heart rhythm, vegetative tone, sympathotonics, normotonics, vagotonics.