We consider a mixed problem for a nonlinear ultraparabolic equation that is a nonlinear generalization of the diffusion equation with inertia and the special cases of which are the Fokker-Planck equation and the Kolmogorov equation. Conditions for the existence and uniqueness of a solution of this problem are established.Ultraparabolic equations arise in the investigation of Markov diffusion processes and scattering of electrons, in financial mathematics, etc. (see, e.g., [1][2][3] and references in [4,5]).The Cauchy problems for linear ultraparabolic equations that are generalizations of the diffusion equation with inertia and for equations that describe processes in financial mathematics were considered in [4][5][6][7][8]. For their investigation, the theory of Lie groups and properties of volume potentials were used.Mixed problems for linear and nonlinear ultraparabolic equations in bounded domains were investigated in [9][10][11][12][13][14]. Under certain conditions imposed on the coefficients, conditions for the existence and uniqueness of solutions of these problems were obtained.In the present paper, we consider a problem in a bounded domain for a nonlinear ultraparabolic equation, which, in particular, contains an unknown function of order q ∈ (1, ∞) and its derivatives with respect to the group of space variables raised to power p ∈ (1, 2]. In contrast to [11][12][13], the hyperbolic part of this equation contains the first derivatives with respect to a group of l + 1, l ≥ 1, independent variables. Also note that it was assumed that p ∈ (2; ∞) in [13] and q ∈ (1, 2) and p = 2 in [12]. The equation considered is a nonlinear generalization of the diffusion equation with inertia, and its special cases are the Fokker-Planck equation and the Kolmogorov equation.Let Ω ⊂ R n and D ⊂ R l be bounded domains with boundaries ∂Ω ∈ C 1 and ∂D ∈ C 1 , respectively, and let n, l ∈ N and T ∈ (0, ∞). We introduce the following notation: τ is an arbitrary fixed time from the segment (0, T ], G = Ω × D,is the outward normal to the surface S T , and ∂G is the boundary of the domain G.We consider functions that satisfy the following conditions:(A) a i ∈ L ∞ 0, T ; C(G) , a i (x, y, t) ≥ a 0 for almost all (x, y, t) ∈ Q T and all i ∈ {1, . . . , n}, and a 0 is a positive constant;(P) the numbers p and q are such that q ∈ (1, ∞) and p ∈ (1, 2];(C) c ∈ L ∞ (Q T ), c(x, y, t) ≥ c 0 for almost all (x, y, t) ∈ Q T , and c 0 is a constant;