The incidence and prevalence of inflammatory bowel diseases (IBD) is growing in parallel with the obesity pandemic. The geography of the distribution of obesity and IBD on the planet have common features. In recent years, there has been information about the epidemiological interaction of predisposing factors to obesity and ulcerative colitis (UC). The aim of the study was to assess the prevalence of overweight and obesity in patients with UC in the Western Siberia region. Materials and methods: a case-control study of 165 ulcerative colitis was conducted in 56 healthy volunteers of comparable gender and age. Body mass index (BMI) was calculated using the formula: weight (kg)/weight (m2). Results: only in 7.9% of patients with UC BMI corresponded to a lack of body weight, in 48% BMI within normal parameters, in 43% of cases BMI corresponded to overweight and obesity. At the same time, the average values and median BMI in UC patients with acute and chronic course of the disease are close to the upper values of normal values. There are no gender differences in BMI compared to the control group. The BMI of patients with severe attack is significantly less than the BMI of patients with moderate attack. Hormonal dependence and resistance, the use of GIBP did not have a significant effect on the BMI of UC patients. In patients with UC, when compared with the control group, there are significantly more patients with type 2 diabetes mellitus. However, there was no significant relationship between the severity of the current attack among UC patients and the presence of type 2 diabetes mellitus in them. When comparing the group of patients with UC with the control group, there were no significant differences in the frequency of occurrence of NAFLD, cholelithiasis, coronary heart disease, arterial hypertension, while in patients with continuously recurrent UC, liver damage characteristic of NAFLD is significantly more common.

The goal of research is to study the influence of the initial state of left ventricular myocardium, as well as the technical features of the coronary artery bypass graft (CABG) on the prognosis of the functioning of coronary shunts.Materials and methods. 46 men, who had CABG for stable angina class III, were examined. 23 of them had 2 type diabetes mellitus (DM2), 23 of them did not have carbohydrate metabolism disorders. On the eve of the surgery, all patients underwent transthoracic echocardiography to determine the indicators of left ventricular function. Information about the technical features of the CABG were taken from the surgical reports. One year after the surgery, all patients underwent a coronary and bypass angiography.Results. Occlusion of coronary shunts was detected in 10 patients with DM2, and in 6 patients without DM2 (p value for Fisher’s exact test is 0.177). A larger left ventricle end-diastolic and end-systolic diameter (p value for the Mann-Whitney test is 0.004; 0.012), as well as a larger left ventricle end-diastolic and end-systolic volume (p value for the Mann-Whitney test is 0.012; 0.006) were associated with the presence of coronary shunt occlusions in patients with DM2. Also in the group of patients with DM2, sequential venous shunts were significantly more frequently occluded (p value for Fisher’s exact test is 0.004). Dysfunctioning shunts were associated with abovementioned figures among patients without carbohydrate metabolism disorders.Conclusion. The results of the research confirm the mutual confounding influence of risk factors on the prognosis after CABG