Boron Neutron Capture Therapy (BNCT) is a nuclear application to cure cancer by using the interaction between the boron compound and the slow (thermal and epithermal) neutron beam obtained from the neutron source. The previous feasibility study shows that the thermal column can generate higher thermal neutrons for BNCT application at the TRIGA MARK II reactor. Currently, the BNCT facility is planned to be developed at the thermal column. Thus, to fabricate the nuclear application such as BNCT required several required such as the study of design, material, neutron desired and safety for the application. Therefore, the use of simulation software such as Monte Carlo N-Particle (MCNP) was extensively essential to identify and determine the most convenient design of the BNCT facility with proper safety requirement standard. Besides that, the simulation also useful in terms of identifying good material and best geometry and the uses of simulation can guide to make sure this research achieves the best results. Generally, MCNP function to track the particle over its energy range using the irradiation transport and the neutron flux and the gamma flux produced from the simulation using MCNPX code was consider right if the relative errors contributed was lower than 5%. This research simulates that the uncovered collimator provides high neutron flux and high collimator performance compared to the fully covered collimator. This research is useful in the simulate on the desired neutron from the BNCT facility design at the TRIGA MARK II reactor.
The thermal column at the TRIGA PUSPATI (RTP) research reactor can produce thermal neutron. However, the optimization on the thermal neutron flux produced should be performed to gain a sufficient thermal neutron for boron neutron capture therapy purpose. Thus, the objective of this review is to optimize the thermal neutron flux by designing the collimator with different materials at the thermal column. In order to fulfil the requirement, set by the IAEA standard, the study of BNCT around the world was being reviewed to study the suitable measurement, material, design, and modification for BNCT at the thermal column of TRIGA MARK-II, Malaysia. Initially, the BNCT mechanisms and history was review. Then, this paper review on the design and modifications for BNCT purpose around the world. Based on this review, suitable material and design can be used for the BNCT in Malaysia. Moreover, this paper also reviews the current status of BNCT at the RTP with the measurement of the thermal neutron flux was conducted along the thermal column at 250 kW. The thermal column of RTP was divided into 3 phases (Phase 1, Phase 2 and Phase 3) so that an accurate measurement can be obtained by using gold foil activation method. This value was used as a benchmark for the neutron flux produced from the thermal column. The collimator was designed using different types of materials, and their characteristic towards gamma and neutron flux was investigated. The reviewed demonstrated that the final thermal neutron flux produced was significantly for BNCT purpose. Lastly, this paper recommends the future research can be conducted on BNCT at RTP.
The development of the Boron Neutron Capture Therapy (BNCT) facility in Malaysia can be performed at the thermal column of the Malaysia research reactor. TRIGA MARK II is one of the facilities that can provide neutron source for BNCT facility. The specification of neutron flux and the gamma dose rate must consider for the development of the BNCT facility as a safety precaution for this research. Based on previous research, the thermal column identified as a suitable place for BNCT facility. To design the neutron collimator for BNCT purpose, the characterization of material towards thermal neutron flux explored using TLD and Microspec-6 and the collimator design was simulate using Monte Carlo N-Particle (MCNP) software based on the characterize materials in order to produce high thermal neutron flux. The combination of lead, HDPE, 30% borated polyethylene and aluminium as collimator design D1 simulate the highest thermal neutron 1.5770 x 109 neutron.cm−2s−1 and suitable for BNCT research purpose at the thermal column.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.