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The article considers the interdisciplinary approach as an interdependent system of knowledge integration, expressed in research and teaching of international relations. It is proved that the discipline of "International Relations" has gone through several stages in the implementation and development of other sciences methodologies to explain and study the evolution of international relations. The most influential ones are political science, history, sociology, but the achievements of the natural and exact sciences are widely used. At the same time, there is a discourse between political science and historical approaches to the analysis of international relations. This is especially pronounced both in the field of theory and in research methods.