We have measured concentrations of ciprofloxacin in serum, hepatic tissue, gallbladder, and bile in 10 patients after a single oral dose of 750 mg given before cholecystectomy. Mean liver and gallbladder tissue concentrations were 12.76 micrograms X g-1 +/- 2.79 (SEM) and 5.94 micrograms X g-1 +/- 1.35, respectively. Concentrations in bile taken from the gallbladder (7 patients) ranged from 68 to 225 micrograms X ml-1, with a mean bile/serum concentration ratio of 49. Concentrations in bile taken from the common bile duct (2 patients) were 17 and 16 micrograms X ml-1.

This paper is concerned with the centrality of aspect seeing in Wittgenstein's philosophy, with some analogies between religious beliefs and aspect seeing, and with the implications of these analogies for the question of the justification of religious beliefs. If belief in God is neither a hypothesis nor a regular perceptual belief but rather a type of aspect seeing, then the kinds of proofs and justifications that are applicable to it would have to engage the non-believer in a manner that would help her experience the dawning of a new aspect. This is why the standard philosophical proofs for theism, even when accepted as valid, are likely to be unsuccessful in bringing about faith.

No abstract

The purpose of this paper is to bring together two thinkers that are concerned with the limits of what can be said, Wittgenstein and Maimonides, and to explore the sense of the good life and of the mystical to which their therapeutic linguistic work gives rise. I argue that despite the similarities, two different senses of the “mystical” are brought to light and two different “forms of life” are explicated and recommended. The paper has three parts. In the first part, I discuss certain key components in Wittgenstein’s early philosophy and the sense of the mystical to which they give rise. In the second part, I discuss Maimonides’ negative theology and its implications for his conception of the via mystica. I end, with a discussion of the relation between the two ideals and its significance.

No abstract