64 ischemic stroke patients with angiographically verified occlusion of the internal carotid artery were studied. 32 patients underwent surgical revascularization in the acute stage within a few hours of acute onset of stroke. 32 patients had conservative management of treatment. Both groups were compared in regard to mortality rate, functional recovery and clinical findings or neurological deficits and psychiatric disturbances on admission and 4 weeks later. Correlations of functional recovery between the two groups showed no significant differences. Mortality rate in the conservatively managed group however was significantly lower than in the operative group.

No abstract

The gluing of tissue with highly concentrated fibrinogen, designated in the following briefly as fibrin gluing, is a relatively old technique. Bergel already reported in 1909 on first trials of hemostasis with fibrin powder. 1 In 1915, Grey used a fibrin solution prepared from sheep blood for hemostasis in intracranial operations. 2 In 1944, Cronkite fixed skin transplants with a fibrinogen-thrombin mixture. Difficulties occurred with the adhesivity, probably in consequence of low fibrinogen concentrations. 3 Since the experimental and clinical investigations of Spängler et al., 4,3 a large number of possible applications of fibrin gluing has been described. 6-12