Phenomenological insomnia types characteristic of neurotic anxiety disorders and their relationship with types of intrapersonal conflicts are described. A quantitative analysis of the dynamics of symptomatic complains, anxiety level, and insomnia is presented. The efficacy of the both psychotherapeutic treatments is shown. However the personality oriented (reconstructive) psychotherapy has demonstrated better and more stable results. This can be explained first of all by its pathogenesis-oriented nature and involvement of the cognitive emotional and behavioral spheres as well as the resolution of the intrapersonal conflicts, which are the cornerstone of neurotic disorders.

The pineal gland is a small and poorly studied neuroendocrine gland located in the epithalamus. There is growing interest in the pineal gland due to its role in regulating human biological rhythms, which is associated with melatonin production, and its close neuroendocrine link between the brain's hormonal and neurally mediated activity. The paper examines the anatomical and physiological features of the pineal gland, its structural variations, and the role of the melatonin it produces in the pathogenesis of several mental and neurological disorders.

The aim of the study was to summarize research data on depressive disorders in dementia and to clarify the presence of their impact on mortality rates in dementia. Materials and methods: To compile a literature review on the keywords “dementia”, “mortality” and “depression”, papers were selected and analyzed in the MEDLINE/PubMed and eLibrary databases from 2000 to 2020, as well as relevant references of the analyzed papers. Of the 245 Russian-language and 142 English-language papers, 64 publications were selected for further analysis. Results: the relationship between depression and dementia in late life is complex and is still under debate. Depression can be both a risk factor for the development of dementia and prodromal syndrome, or accompany the development of dementia. Depression is common in all types of dementia and in all stages of the disease, including mild cognitive impairment. Depression and vascular dementia may have a synergistic effect on mortality. Conclusion: the results obtained in the course of the study are important for integral understanding of the peculiarities of managing patients with various types of dementia.

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Non-motor symptoms are common in Parkinson`s disease and reflect the multisystem nature of the disorder. Parkinson’s disease is highly heterogeneous in early clinical features and later outcomes. This makes classifying genetic subgroups of PD relevant to clinical research and practice, particularly if they are prognostically relevant. Non-motor sypmptoms may be detrimental to patients’ functional status and sense of well-being.