Background: Weight loss medications that were traditionally considered safe and effective are associated with severe adverse effects. Aim: The present work seeks to disseminate awareness about the effectiveness and safety of weight loss medications. Methods: A descriptive cross-sectional study was performed across the seven Emirates of the United Arab Emirates involving 250 registered pharmacists.Pre-designed open-ended questionnaires comprising of four sections were employed to collect responses from the pharmacists. Results: The mean responses indicated that 98% of pharmacists dispense prescription weight loss medications, and 96% of the pharmacists also stock herbal products. The number of pharmacists who provided patient counselling was 32.7% from which feedback was received in 59.2% of cases after the administration of medications. Pharmacists' opinions on the occurrence of adverse effects can be rank ordered as kidney stone > diarrhoea > hypertension > dizziness > weakness > fever. Physical activity and diet control were the preferred weight loss measures. In all, 81.8% reasoned that prescription weight loss products have severe adverse effects and their use should be restricted, thereby leading to the low recommendation level (30.21%). In comparison, 93% believed that adverse effects of herbal products are less. Healthy weight management services were available in only 10.96% of pharmacies although 98.3% of participants recommended such services. Conclusion: The knowledge void pertaining to the use of herbal medications and weight management was discerned in this study and rigorous and quality training for healthcare professionals is proposed. Figure 2Scatter plot of pharmacist belief in the possibility of adverse effects arising during the use of herbal weight loss products.