To analyze our experience with 105 cases who underwent plasmapheresis for various disorders. Materials and Methods:-Retrospective review of Plasmapheresis(PE) was done over a period of 13 years, from july 2015 to August 2002 in a tertiary care centre. Results:-The main indication for PE was GuillainBarresyndrome(GBS) (31%). Age of patients ranged from 18-62 years. The most common complications were paraesthesias and/or cramps (36.1%) and hypocalcemia (7%).There was no mortality related to the procedure. Conclusion:-The analysis of 105 cases of plasmapheresis in our department showed that the procedure is safe, with only minimal procedure related complications and no mortality.

Marine transportation is still the primary source of global transportation. The propeller, which is a critical componentof the propulsion system, must be designed with multiple constraints and objectives to satisfy the need. Recent studies propose that utilizing an improved optimization algorithm and computational analysis would explore better designs than conventionalmethods. In the present study, Elitist Particle Swarm Optimization (EPSO) technique is implemented to optimize the design ofa marine propeller. Potsdam’s Conventional Propeller VP 1304 is used as a benchmark design case. Reynold’s Averaged NavierStokes equation based Computational Fluid Dynamics (CFD) along with Vortex Lattice Method (VLM) and Fluid StructureInteraction (FSI) model is used for computational analysis. The results obtained in this study are validated against the previously published experimental data. An optimized propeller design is proposed based on the Elitist Particle Swarm Optimization technique.It is observed that the proposed design shows improved open water performance for lower advance coefficient (J) valuesbased on the given constraints. It’s also observed that open water efficiency is improved by 7 percent for J=0.6 compared tothe original design. The one-way Fluid Structure Interaction analysis shows that the proposed design is structurally stable underopen water test conditions