Objective: To determine the radiological parameters of COVID-19 patients based on CO-RADS classification and to compare the RT-PCR with chest CT. Materials and Methods: This cross sectional study involved 180 participants who were hospitalised in COVID Unit of Farooq Hospital, West Wood, Lahore from April 2020 to July 2020. Data was collected from suspected COVID-19 patients who were subjected to CT chest and RT-PCR. SPSS version 22.0 was used to analyse the data. Frequency and percentages were calculated for categorical variables while mean and standard deviation was calculated for numerical veriables. Results: Of the total 180 patients, there was frequent manifestation of ground-glass opacities (GGOs) 168 (93%) followed by consolidation 121(67%) and reticulation/thickened interlobular septa 41 (23%) in radiological features of our study. Whereas, nodular lesions were completely absent. The highest number of patients 132 (73%) were in CO-RADS 5 classification. GGOs 126 (95%); and consolidations 93 (77%) were also highest in CO-RADS 5. Only 143(79%) of total RT-PCR tests were positive when compared with chest CT 158(88%). Conclusion: CO-RADS categorical assessment scheme indicates a significant prevalence of GGOs in COVID-19 patients. RT-PCR of most of the patients was negative at the time of admission but on radiological analysis they had positive CT findings suggestive of COVID-19.

Aim: To assess the baseline renal profile of patients with COVID-19. Methods: It was a cross sectional study, conducted in hospitals of Rawalpindi Medical University from March to August 2020. Consecutive 169 confirmed cases of COVID-19 were enrolled. Patients with history of kidney disease were not included. Peripheral blood samples were analysed for renal functions on fully automated chemistry analyser. Estimated glomerular filtration rate (eGFR) for every patient was calculated using two equations for chronic kidney disease epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD). Results: Out of total 169 COVID-19 patients, 97(57%) were males 72(43%) were females. The mean age was 54.1±16.30 (18 to 92) years. A total of 96(57%) patients were below 60 years of age. Mean Urea, serum creatinine (Scr) and blood urea nitrogen (BUN) were found to be elevated in this study cohort with no statistically significant difference with respect to age and gender (P value >0.05). Scr was raised in 46(27%) while 113(67%) and 103 (62%) patients had elevated serum Urea and BUN respectively. eGFR of <60mL/min/1.73m2 was observed in 50(30%) of patients. Conclusion: Elevated mean Urea, Scr and BUN were observed in COVID 19 patients without any significant difference according to age and gender. Moderate to severe derangement in eGFR was noted in one third of COVID 19 patients. Keywords: COVID-19, Renal function test, Estimated glomerular filtration rate