Objective/Background: Lymphoma is a common human cancer that shows a variable geographic incidence worldwide. It is the fourth most common cancer in Jordan. Systemic reports of descriptive epidemiology on lymphoma from the Middle East are limited. Methods: A nationwide multi-institutional retrospective study was conducted covering all major hospitals and laboratories that provide diagnostic services. We collected data on all cases diagnosed with lymphoma between 2014 and 2019. The included variables were patients’ age, gender, anatomic site, and the histologic type according to the World Health Organization classification system. Results: A total of 4189 cases were diagnosed with lymphoma. There was a statistically significant gender difference (p < .05), as 57.5% of patients were males. The peak incidence occurred at age 25-55 years. There were 1,652 (39%) cases of Hodgkin lymphoma (HL) and 2,537 (61%) of non-Hodgkin lymphoma (NHL), where nodular sclerosis (67%) and diffuse large B-cell lymphoma (53%) were the most common subtypes, respectively. The average age-adjusted incidence rates per 100,000 population were 8.01 for all lymphomas, 4.33 for NHL, and 3.16 for HL and all remained stable over the 6 years. Conclusion: HL is the most common lymphoma in Jordan, with a percentage higher than most of reported studies in Asian and Western countries. It also shows a unimodal distribution of age-specific incidence rates, with a single peak in young adults. The incidence rate of HL is higher than Eastern countries but comparable to the West. In contrast, NHL demonstrates a lower incidence rate than Western countries but a similar distribution of subtypes, as mature T/natural killer-cell lymphomas were rare.

Background: Ancient trigeminal schwannomas are extremely uncommon benign tumors. Such tumors are longstanding, slow growing and may demonstrate seemingly malignant features irrespective of its benign nature. The tumor may involve the trigeminal nerve root, the trigeminal ganglion, or any of its peripheral branches. Its clinical presentation may include trigeminal neuralgia, blurry vision, diplopia, or even seizures. Surgical excision is the mainstay of treatment with definite diagnosis only by histopathology. Case Description: We described a case of a 35-year-old female presenting with recurrent episodes of generalized seizure and left-sided weakness. Brain imaging showed a right temporal space occupying lesion. Results of histopathology were consistent with trigeminal schwannoma associated with ancient histopathological changes. Complete tumor excision was achieved by a two-stage craniotomy, which led to the patient’s condition to dramatically improve. Conclusion: Ancient trigeminal schwannomas are easily diagnosed through histopathology and result in favorable clinical outcomes after total microscopic surgical excision. A high suspicion index of ancient schwannoma diagnosis should be derived from the patient’s presenting clinical picture and the classical findings derived from neuroimaging.

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