Aim: Our study aimed to assess and prevent acute stress disorder in women with pregnancy loss. Materials And Methods: Pregnant women presenting to the Department of Obstetrics and Gynecology at level 2 centers between March 2019 and March 2021 were included in the study. Women with pregnancy loss of fewer than 21 weeks were assigned to the "pregnancy loss group" and women with healthy pregnancies were assigned to the "control group." Participants were asked to complete a questionnaire. The questionnaire included questions about pregnancy history, sociodemographic data, and medical history. After the questionnaire, patients were asked to complete the post-traumatic stress disorder (PTSD) scale. Of the patients who participated in the study, 91 (35%) were in the pregnancy loss group and 156 (65%) were in the control group. Statistically, p < 0.05 was considered significant. Results: The mean age of the patients with pregnancy loss was 27.52±5.60 years, whereas the pregnant women in the control group were 26.43±5.44 years old. The mean age of the two groups was similar (p=0.656). The PTSD score of the participants was 33.10±9.3 (min=15, max=49). The mean PTSD score of the cases who suffered pregnancy loss was 36.23±9.49 and 31.12±7.34 in the control group. The PTSD score of the group with pregnancy loss was significantly higher than that of the control group (p=0.003). Conclusion: In our study, symptoms of acute stress disorder were found to be more common in women who experienced pregnancy loss. Couples who have suffered pregnancy loss should receive social and psychological support. Psychological support and counseling are very important for the couple's psyche. In this way, the woman's disorder can be prevented from developing into post-traumatic stress disorder.