Onychomycosis is a chronic fungal infection of the nail, characterised by nail discoloration, subungual hyperkeratosis and onycholysis.The involved pathogens are dermatophytes, yeasts (Candida spp.) and non-dermatophyte moulds (NDMs). 1 Dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes are the most common agents of onychomycosis, with higher prevalence of the infection in toenails than in fingernails. Candida albicans affects almost exclusively the fingernails and accounts for 10% of toenail onychomycosis. 2,3 Onychomycosis represents a therapeutic challenge because of the high recurrence rate. Moreover, it requires long treatment duration and systemic rather than topical antifungal agent because onychomycosis-related subungual hyperkeratosis limits the penetration with topical antifungal drugs, in addition to the slow nail growth,