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A theoretically and numerically photonic crystal structure with parity-time symmetry is investigated to realize the design of a biomedical sensor for biosensing applications. The transmittance spectra of the structure are investigated, and various performance parameters are evaluated. Different structure parameters such as the unit cell number, the thickness of the sample layer, macroscopic Lorentz oscillation intensity in the PT-symmetry unit cell, the porosity of gallium nitride, and incident angle are theoretically and numerically investigated. To improve the performance of the device, an optimization technique is used. The relatively high sensitivities of 496 nm/RIU (the change in the resonant peak wavelength per refractive index unit) and 1002142 %/RIU (the change in the transmittance of the resonant peak per refractive index unit) are achieved. The proposed device can be a relatively high-precision detection device for biosensing applications.