Although the important role of the non-structural (NS1 and NEP) gene of influenza A in virulence of the virus is well established, our knowledge about the extent of variation in the NS gene pool of influenza A viruses in their natural reservoirs in Kazakhstan is incomplete. 17 influenza A viruses of different subtypes were studied in this paper. Seven types of haemagglutinin and five different neuraminidase subtypes in eight combinations were found among the isolated viruses. A comparison of nucleotide sequences of isolated viruses revealed a substantial number of silent mutations, which results in high degree of homology in amino acid sequences. By phylogenetic analysis it was shown that two distinct gene pools, corresponding to both NS allele A with 5 Clades and B, were present at the same time in Kazakhstan. The degree of variation within the alleles was very low. In our study allele A viruses had a maximum of 5% amino acid divergence in Clade while allele B viruses had only 4% amino acid divergence.

Purpose: to study the impact of swimming classes in a non-profiled university on the health potential and physical fitness of students. Methods and organization of research: standard methods of research of student health indicators, educational testing, questionnaire, expert assessment, observation, mathematical processing of research outcomes. The study involved 40 male students aged 18±1 years of the 1st and 2nd years of study of Kazan State University of Architecture and Civil Engineering, without health restrictions. The participants were divided into experimental and control groups with 20 people in each group. Research results and discussion. At the beginning of the first semester, we identified the indicators of cardiovascular, respiratory system and physical fitness of students. During next four semesters, students of the control group participated in practical classes on the traditional program of physical education for a major group of university students (twice a week for two hours). Students in the experimental group had one traditional class and one swimming class per week. At the end of the fourth semester, we reassessed previously studied indicators for the students in experimental and control groups and compared the outcomes. Conclusion. The research revealed that the implementation of swimming classes in physical education programs of non-profiled universities even in small volumes (once a week for 2 hours) result in the improvement of indicators of student health potential and physical fitness. In particular, the suggested training strategy provided the improvement of the following indicators: cardiovascular indicators according to the Ruthier test and orthostatic test by 18.4% and 21.3% respectively, respiratory indicators according to the Shtange and Genchi test – by 9.1% and 12.5%, physical fitness indicators for the sit-up exercise – by 22.8%, for the push-up exercise – by 15.6%.

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