Three-component reaction between dialkyl acetylenedicarboxylates, trimethylphosphite, and aldehyde semicarbazones leads to functionalised phosphonates in good yields.
Organo-phosphorus compounds S 0080 Stereoselective One-Pot Synthesis of Functionalized Phosphonates by Three-Component Reaction Between Trimethylphosphite, Dialkyl Acetylenedicarboxylates and Aldehyde Semicarbazones. -Advantages of the present method are the neutral conditions and simple mixing of the substances without any activation. -(ANARY-ABBASINEJAD*, M.; ASCARRIAN, N.; J. Chem. Res. 2007, 1, 11-13; Dep. Chem., Islamic Azad Univ., Yazd, Iran; Eng.) -H. Haber 29-155
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