Oral myiasis is more prevalent than commonly believed to be and an astute practitioner should be aware of such maggots in the mouth, in cases of oral and maxillofacial trauma and in vulnerable categories of patients. These patients are not physically or mentally endowed to ward off flies or complain about worms burrowing their way into oral wounds. Occurrences of such cases are rare in developed countries and reflect the lack of special care for the vulnerable group of patients belonging to certain geographic areas.

Giant cell granuloma (GCG) is an uncommon bony lesion in the head and neck region, most commonly affecting the maxilla and mandible and has a female predilection. The clinical behavior of central GCG ranges from a slowly growing asymptomatic swelling to an aggressive lesion. The clinical, radiological, histological features and management of an aggressive GCG of maxilla in an 18-year-old female patient are described and discussed. It is emphasized that surgery is the traditional and still the most accepted treatment for GCG. Le Fort I osteotomy has been advocated as one of the access osteotomy for the surgical management of aggressive and extensive GCG involving the maxilla. The postoperative morbidity and recurrence have been discussed.