Herein, we present a novel silver- or copper-mediated direct amidation–ketonization–selenation of terminal alkynes for the synthesis of α-oxo-selenoamides. The reaction utilized easily accessible elemental selenium as the source of selenium. In addition, the 18O labeling experiment revealed that TEMPO is the oxygen source of the carbonyl group. The reaction takes advantage of an unsaturated CC bond to construct new CO, CSe, and C–N bonds in one step.

Herein, we present a Mizoroki–Heck reaction initiated formal C(sp3)-H arylation of α-methylcinnamaldehydes. The reaction proceeds smoothly under phosphane-free conditions, and provides a facile method to access important α-methylcinnamaldehyde derivatives with...

A novel intermolecular radical addition/cyclization and Se-group transfer reaction of terminal alkynes and unsaturated alkyl selenide is presented which offers a straightforward and facile approach for the synthesis of valuable Se-containing cyclopentenes. Remarkable features of this strategy include easily accessible starting materials, metal-free and peroxide-free conditions, high atom economy, simple operation and broad substrate scope. More importantly, the reaction is easy to scale up and can be extended to the construction of six-membered carbon ring.[a] D.

Organoboron compounds are a class of significant building stocks in synthetic chemistry, due to their powerful transformation ability of C-B bonds. As a special type of organoboronates, α-oxylboronates possess geminal...