Objective The aim of this study was to estimate the incidence of delirium and its risk factors among critically ill cancer patients in an intensive care unit (ICU). Materials and Methods This is a prospective cohort study. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) was measured daily at morning to diagnose delirium by a physician. Delirium was diagnosed when the daily was positive during a patient's ICU stay. All patients were followed until they were discharged from the ICU. Using logistic regression, we estimated potential risk factors for developing delirium. The primary outcome was the development of ICU delirium. Results There were 109 patients included in the study. Patients had a mean age of 48.6 ± 18.07 years, and the main reason for admission to the ICU was septic shock (40.4%). The incidence of delirium was 22.9%. The mortality among all subjects was 15.6%; the mortality rate in patients who developed delirium was 12%. The only variable that had an association with the development of delirium in the ICU was the days of use of mechanical ventilation (OR: 1.06; CI 95%: 0.99–1.13;p=0.07). Conclusion Delirium is a frequent condition in critically ill cancer patients admitted to the ICU. The duration in days of mechanical ventilation is potential risk factors for developing delirium during an ICU stay. Delirium was not associated with a higher rate of mortality in this group of patients.

reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. carbon dioxide 30 [27][28][29][30][31][32][33][34][35] mmHg and median temperature 37.1 [36.8-37.3]°C. After removal of artefacts, the mean monitoring time was 22 h08 (8 h54). All patients had impaired cerebral autoregulation during their monitoring time. The mean IAR index was 17 (9.5) %. During H 0 H 6 and H 18 H 24 , the majority of our patients; respectively 53 and 71 % had an IAR index > 10 %. Conclusion According to our data, patients with septic shock had impaired cerebral autoregulation within the first 24 hours of their admission in the ICU. In our patients, we described a variability of distribution of impaired autoregulation according to time. ReferencesSchramm P, Klein KU, Falkenberg L, et al. Impaired cerebrovascular autoregulation in patients with severe sepsis and sepsis-associated delirium. Crit Care 2012; 16: R181. Aries MJH, Czosnyka M, Budohoski KP, et al. Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury. Crit. Care Med. 2012.

Desde diciembre de 2019, una nueva enfermedad causada por coronavirus 2019 (COVID19), estalló en Wuhan, China. Causante del síndrome respiratorio agudo severo (SARS-CoV2) Algunos casos asocian COVID-19 y trastornos autoinmunes; el papel de este virus en la autoinmunidad esta poco dilucidada. El lupus eritematoso sistémico (LES) es una enfermedad autoinmune. El Baricitinib es una molécula inhibidora de quinasa de Janus (JAK) aprobada para el tratamiento de trastornos autoinmunitarios e inflamatorios, recientemente utilizado para el manejo de la enfermedad grave por COVID-19. Se trata de 4 casos de LES con COVID 19, dos de las cuales ingresaron a la unidad de cuidados intensivos, fallecieron; con antecedente de nefritis lúpica. Los dos casos siguientes sobrevivieron. Aún se desconocen los factores de riesgo que incrementan la mortalidad en LES, sin embargo, se asoció nefritis lúpica con mortalidad en COVID-19. Se requieren más estudios para comprender el riesgo entre las enfermedades autoinmunes y COVID-19.

Introducción: la evidencia en la prevalencia de COVID-19 relacionado con los problemas de salud es una emergencia. Reporte de caso: mujer de 28 años, con TCA (trastorno conductual de la alimentación) desde los 12 años. IMC (índice de masa corporal) 13.6 kg/m2. Hospitalizada por padecimiento respiratorio (broncoespasmo) debido a COVID-19, con oxígeno suplementario dos litros, durante su estancia rechazo a los alimentos, se colocó sonda nasogástrica, iniciando nutrición enteral estándar, presentando síndrome de realimentación (SRL), manejo con electrólitos y se modificó la dieta enteral baja en carbohidratos, alta en proteínas y terapia psicológica por videollamada. Recuperando estado de salud y egreso a domicilio. Discusión: las complicaciones de realimentación aumentan cuando se inicia una tasa calórica alta. La fórmula enteral estándar contiene 54% de carbohidratos, el cual contribuye al riesgo de desarrollar SRL. Se desconocen las consecuencias de TCA y COVID-19 y es probable que se vuelva más evidente con el tiempo.