New quinoline-based thiazole derivatives
QPT
and
QBT
were synthesized and characterized
by various spectroscopic
and single-crystal X-ray crystallographic studies. The metal-sensing
properties of the probes were further examined by absorption and fluorescence
spectrometry. The fluorescence intensity of
QPT
and
QBT
was remarkably quenched during the addition of Fe
3+
, Fe
2+
, and Cu
2+
ions in THF/H
2
O (1:1) at pH = 7.4 in HEPES buffer, while the addition of
other metal ions did not affect the fluorescence intensity of the
ligands. The detection ability of the probes
QPT
and
QBT
was further investigated by titration with various equivalents
of metal ions, optimized pH ranges for detection, and reversibility
with Na
2
EDTA for biological applications.
One‐step microwave‐assisted synthesis of dihydro dibenzophenanthrolines are reported using a self‐catalyzed Friedlander reaction. The reaction is carried out in one step by simple microwave irradiation of 3,4‐dihydroacridin‐1(2H)‐one with 2‐amino‐benzophenone in the presence of acid catalysts with solvent‐free conditions. Thin‐layer chromatography was used to monitor the progress of the reaction; hence, it was observed that the reaction starts slowly and accelerates as it proceeds to ring fusion transformation. Synthesized compounds' isolated yield is enhanced in the absence of solvent systems with Friedlander catalyst under microwave irradiations.
The cover image is based on the Article Microwave‐assisted Synthesis of Dihydro Dibenzophenanthroline and Its Derivatives Using a Self‐catalyzed Friedlander Reaction, by Suresh Thangaraj et al., https://doi.org/10.1002/jhet.3339.
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