Key words：lanthanum carbonate, phosphate 〈Abstract〉Lanthanum carbonate chewable tablets can be administered without water. However, it has been reported that phosphate(P)absorption varies according to the degree of chewing of the lanthanum carbonate tablet. To resolve this problem, a granule formulation of lanthanum carbonate has been released. We investigated P absorption when the new granule formulation of lanthanum carbonate was administered. We administered the granule formulation of lanthanum carbonate to 18 hemodialysis patients previously treated with a chewable tablet formulation of lanthanum carbonate. The mean serum P concentration significantly declined from the initial level of 5.69±0.86 mg／dL to 5.38±0.86 mg／dL at two weeks and to 5.20±1.20 mg／dL at four weeks. When the daily dose of lanthanum carbonate was higher, the decrease in the serum P concentration might be larger. No significant changes were seen in the serum calcium(Ca)or intact parathyroid hormone(iPTH)levels.