It is known that intuitionistic Kripke semantics can be generalized so that it can treat arbitrary propositional connectives characterized by truth functions. We extend this generalized Kripke semantics to first-order logic, and study how the choice of connectives changes the relation between intuitionistic predicate logic and the logic of constant domains in terms of validity of sequents. Our main result gives a simple necessary and sufficient condition for the set of valid sequents in intuitionistic predicate logic to coincide with the set of valid sequents in the logic of constant domains.
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