REF/2016/07/011808.

BACKGROUND Dyslipidaemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. It has been seen in many trails and studies that good glycaemic control has prevented the cardiovascular morbidity and mortality. The rationale of this study was to detect the lipid abnormality in diabetic patients. MATERIALS AND METHODS This cross-sectional observational study was conducted to estimate prevalence of dyslipidaemia among diabetic patients of KIMS, Hubli. A total of 100 patients were included out of which 62 were males and 38 females. RESULTS There was a positive correlation between PPBS and dyslipidaemia with p value=0.01. However, when correlation between dyslipidaemia and duration of diabetes was compared, it was not significant with p value of 0.64. CVS status, elevated urea and elevated creatinine were not significant when compared to dyslipidaemia. Parameter correlated between capillary and venous estimate showed that the total cholesterol, triglyceride, LDL, VLDL and HDL were highly significant with p value <0.001. CONCLUSION Our study showed that there is increased incidence of dyslipidaemia in diabetes patients. Hence, constant monitoring of lipid profile is required in diabetes patients to reduce the risk of CVS diseases.

BACKGROUND DM is characterized by insulin resistance and dyslipidaemia, in particular, high levels of total cholesterol, triglycerides and LDL, and low levels of HDL-C, which confers increased risk for CAD that may manifest as life threatening ACS. We wanted to study the correlation between HbA1c & total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL) in diabetic patients presenting with acute coronary syndrome and also their correlation with severity of ACS independently. METHODS Blood samples of 50 known diabetic patients presented to emergency with ACS were sent for HbA1c & lipid profile estimation. All patients underwent coronary angiography. Obtained results were statistically analysed & correlated. RESULTS Statistically significant direct co-relationship was found between HbA1c, LDL, Total cholesterol, ACS severity (SVD/MVD) & inverse co-relationship with HDL. CONCLUSIONS In our study we concluded that there is strong correlation between HbA1c and dyslipidaemia, with severity of coronary artery disease. HbA1c, total cholesterol, LDL cholesterol are directly proportional and HDL cholesterol is inversely proportional to the severity of coronary artery disease. Hence incidence of ACS can be minimized with adequate glycaemic control.

BACKGROUND Aim-Coronary artery disease is one of the common cause of death all over the world. There have been only few studies done regarding non-invasive predictors and prevalence of left main (LMD) or triple vessel disease (TVD) in patients with CAD. Uncertainties still exist about their prevalence and predictors in patients with CAD. Our aim was to detect non-invasive predictors, prevalence and clinical profiles of LMD/TVD patients.

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