A series of previously conducted experiments pertaining to various chemicals and drugs uncover a natural linkage between the molecular structures and the bio-medical and pharmacological characteristics. The forgotten topological index computed for the molecular structures of various chemical compounds and drugs has proven significant in medical and pharmaceutical fields by predicting biological features of new chemical compounds and drugs. A topological index can be considered as the transformation of chemical structure into a real number. Dendrimers are highly-branched star-shaped macromolecules with nanometer-scale dimensions. Dendrimers are defined by three components: a central core, an interior dendritic structure (the branches), and an exterior surface with functional surface groups. In this paper, we determine forgotten topological indices of poly(propyl) ether imine, porphyrin, and zinc–porphyrin dendrimers.
Automatic Face Recognition (FR) presents a challenging task in the field of pattern recognition and despite the huge research in the past several decades; it still remains an open research problem. This is primarily due to the variability in the facial images, such as non-uniform illuminations, low resolution, occlusion, and/or variation in poses. Due to its non-intrusive nature, the FR is an attractive biometric modality and has gained a lot of attention in the biometric research community. Driven by the enormous number of potential application domains, many algorithms have been proposed for the FR. This paper presents an overview of the state-of-the-art FR algorithms, focusing their performances on publicly available databases. We highlight the conditions of the image databases with regard to the recognition rate of each approach. This is useful as a quick research overview and for practitioners as well to choose an algorithm for their specified FR application. To provide a comprehensive survey, the paper divides the FR algorithms into three categories: (1) intensity-based, (2) video-based, and (3) 3D based FR algorithms. In each category, the most commonly used algorithms and their performance is reported on standard face databases and a brief critical discussion is carried out.
Sudden unexpected perinatal collapse is a major trauma for the parents of victims. Sudden infant death syndrome (SIDS) is unexpected and mysterious death of an apparently healthy neonate from birth till 1 year of age without any known causes, even after thorough postmortem investigations. However, the incidence of sudden intrauterine unexplained death syndrome (SIUDS) is seven times higher as compared with SIDS. This observation is approximated 40–80%. Stillbirth is defined as death of a fetus after 20th week of gestation or just before delivery at full term without a known reason. Pakistan has the highest burden of stillbirth in the world. This basis of SIDS, SIUDS, and stillbirths eludes specialists. The purpose of this study is to investigate factors behind failure in control of these unexplained deaths and how research may go ahead with improved prospects. Animal models and physiological data demonstrate that sleep, arousal, and cardiorespiratory malfunctioning are abnormal mechanisms in SIUDS risk factors or in newborn children who subsequently die from SIDS. This review focuses on insights in neuropathology and mechanisms of SIDS and SIUDS in terms of different receptors involved in this major perinatal demise. Several studies conducted in the past decade have confirmed neuropathological and neurochemical anomalies related to serotonin transporter, substance P, acetylcholine α7 nicotine receptors, etc., in sudden unexplained fetal and infant deaths. There is need to focus more on research in this area to unveil the major curtain to neuroprotection by underlying mechanisms leading to such deaths.
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