Computerized insulin dosing software provides decision support in the form of pattern management identification, standardized dosing, and ease of use in both the inpatient and outpatient settings. The purpose of this analysis article is to review the features of all three electronic glycemic management systems available in the United States and to discuss the potential benefits of an automated insulin dosing system compared to a paper protocol or electronic order set. Four articles will be presented in this inpatient focused issue that examine the safety and efficacy of the Glytec® eGlycemic Management system in a variety of patient populations.