Background: Cervical cancer is a preventable lesion that can be identified by stepwise screening methods. Visual inspection of the cervix with acetic acid, Lugol’s iodine, pap smear, and HPV are the primary screening methods. This study aims to evaluate the efficacy of the Swede score in predicting high-grade lesions of the cervix among patients attending a colposcopy clinic. Methods: This observational cross-sectional study was performed in a colposcopy clinic under the department of obstetrics and gynaecology at CMCH. All referral patients to the colposcopy clinic were the study population. Women aged between 25-65 years was the study subject. Results: Majority (47.5%) of the patient’s Swede score was 4 and 20.1of % of patients had scores of 5-6 and only 1.3% of patients had scores ≥7%. 63 (79%) patients had low grade/normal/ cervical intraepithelial lesion (CIN) 1, 16 (20%) patients had high grade/non-invasive cancer/CIN 2 and only 1 patient had high grade/suspected invasive cancer/CIN 3. A score of 6 had a specificity of 100% for CIN 2 with a sensitivity of 30% positive and negative predictive value (PPV=100%; NPV=90.9%). Lowering the score to 5 for predicting CIN 2 improved the sensitivity at the expense of specificity (sensitivity=60%; specificity=90%; PPV= 94%; NPV=46.2%).Conclusions: Swede scoring system is consistent and reproducible, has a simple structure, and thus contributes to preventing cervical cancer. Swede score of 6 or more has 100% specificity; this scoring method is a preferred method for the treatment of high-grade CIN.

Magnesium deficiency during pregnancy has been reported to be associated with eclampsia. This descriptive cross sectional study carried out in Obstetrics and Gynecology Department of Chittagong Medical College Hospital from September 2013 to August 2014. The objective of the study was to estimate the serum magnesium level in eclamptic patients. Serum magnesium level of 80 eclamptic patients and 80 healthy pregnant women (Age and gestational age matched) were measured and compared to evaluate the association between hypomagnesaemia and eclampsia. All the necessary information and clinical data were recorded in predesigned questionnaires and analyzed using SPSS. t-Test and Chi-square test were used for comparison of quantitative and qualitative data respectively. For analytical test the level of significance was 0.05 (‘p’ value <0.05 was considered significant). Serum magnesium level was found below normal (<1.9mg/dl) in 93.75% eclamptic patients whereas in case of healthy pregnant women 73.75% had serum magnesium level within normal range (1.9-2.5mg/dl). The mean serum magnesium level (1.05±0.29mg/dl) was significantly (p<0.05) lower than the mean serum magnesium level of healthy pregnant women (2.19±0.35mg/dl). Significant difference of serum magnesium level between eclamptic patients and healthy pregnant women recommends that there may have some relationship between hypomagnesemia and development of eclampsia. JCMCTA 2016 ; 27 (2) : 18 - 23