A case of a pediatric patient with a recurrent single lesion, four months after finishing treatment for seven lesions of cutaneous leishmaniasis with intramuscular meglumine antimoniate. Once the recurrence was confirmed by direct visualization of amastigotes, the decision taken was to repeat treatment with 1 cc of intralesional meglumine antimoniate, with a uniform distribution inside the lesion and one week interval between each application. After four sessions of intralesional treatment, the patient meets curation criteria. The patient was discharged with follow-up appointment up to seven months after the treatment was finished, there was no evidence of recurrence.