No abstract

INTROduCTIONRectal neuroendocrine neoplasms (rNENs) are small tumors that are currently being found at an increasing frequency during colonoscopy examinations. 1 These are usually G1 lesions, of less than 10 mm in diameter, derived from the muscularis mucosa, which grow into the submucosa and deeper layers. Their subepithelial origin is the reason why simple snare or biopsy forcep polypectomy is usually an ineffective method of treatment. Thus, more advanced methods such as endoscopic mucosal resection

The case of a 76-year-old patient, with a history of melanoma, admitted to the department of gastroenterology with symptoms of hypovolemic shock, caused by massive  gastrointestinal bleeding. Clot-covered melanoma metastases were detected in both gastroduodenoscopy and colonoscopy. Gastrointestinal melanoma metastases are found in the majority of patients with advanced melanoma during autopsy; however, they are rarely detected in intravital studies and can be misdiagnosed as other benign lesions in endoscopy. In cases of patients with history of melanoma, metastases should be considered as the cause of non-specific abdominal symptoms, anemia, or bleeding from the gastrointestinal tract.