The pattern of traumatic death is a subject of great interest in the worldwide literature. Most studies have aimed to improve trauma care and raise awareness of avoidable fatal complications. The objective of present study was an epidemiological and clinical analysis of causes of traumatic death of the patients treated in Multitrauma Centre of the University Teaching Hospital no 1 in Szczecin, over a period of 3 years (2017-2019). Material of the study comprised of medical data of 32 patients in a mean age of 63 years, who died following polytrauma injury. Time of death form admission to the Multitrauma Centre, primary cause of death, spectrum and sites of injuries, as well as method of treatment (operative or conservative) were variables considered in the analysis. Results. The predominant mechanisms of injury were traffic accidents - 22 cases (69%) followed by falls from height 8 (25%) and other mechanism - 2 cases (6%). The most common primary cause of death was brain injury - 17 patients (53%) followed by pelvic or spine fractures - 5 (16%). The predominant constituents of polytrauma were bony injuries (pelvis, spine and limbs) - 28 cases (87%), followed by head injuries - 25 (78%), chest - 24 (75%) and abdominal injuries - 17 (53%). Eighteen patients (56%) required operative treatment; craniotomy for brain injuries was the most commonly performed - in 11 patients followed by laparotomy - in five. Five other patients underwent endovascular procedure - embolization of pelvic arteries. Twelve patients (38%) died in the first two days from admission to the trauma centre, five (16%) in the first week and 15 later than one week form admission. Conclusions. Head injuries, pelvic fractures with associated retroperitoneal bleeding and severe injuries affecting several body parts were identified to be the most dangerous for polytrauma patients’ survival. A trend to decrease mortality due to haemorrhagic shock was observed, but it remains unchanged for central nervous system injuries.