The human well-being directly depends on the economic state and continuous increasing the volume of output. Specialists of different scientific fields are studying the possibilities of growing the efficiency of production processes. Increasing the volume of output is related to the widespread automation of the manufacturing. The motor functions of workers are decreased on the background of the introduction of automated labor: static repetitive moves are prevailed; also it is associated with work on a personal computer. At the same time, blood supply of the body is impaired; the working efficiency is decreasing. Analysis of the basic factors affecting labor productivity is presented in this paper. These factors are age and sex signs, the level of physical activity of workers, working conditions, etc. Results of this research presents that regular physical exercises are main factor for increasing labor productivity of company workers (study was carried out based on the worker's data of Public Corporation "Tyumen OilResearch Center", Tyumen (TORC)). This company is mainly engaged in scientific research. The production activity of personnel has a physical activity low level in the workplace under such conditions. Also, it is shown that systematic physical load of workers leads to lower number of colds. In this regard, the number of days of incapacity for work is reduced; it increases the production process efficiency. Thus, it is necessary to popularize a healthy lifestyle and systematic physical exercises to improve the wellbeing and health of employees.