The article deals with the issues of ensuring the competitiveness of enterprises by means of the network interactions. The aim of the research is to study the problem of choosing the effective toolkit for managing the development of the manufacturing enterprises based on the inter-organizational integration processes. The issues of integration with other market participants, which is a prerequisite for ensuring the strategic competitive advantages of the enterprises in the context of globalization, are discussed in the article. The simplified algorithm has been developed to substantiate the feasibility of the method of integrating a business entity with other market participants. As a result of the research, the logic of crosssectoral integration of the enterprises was substantiated through the creation of the networked business systems. They are characterized by flexibility and ability by their nature to adapt to the market space. As a result, the main stages of creating the business network were identified, which presuppose the presence of the key components of its forming. They are missions, goals, resources.