For the first time in scientific literature, this work addresses the current situation of the Ishim River water quality in the Akmola Region (Northern Kazakhstan). This work uses environmental monitoring techniques to analyze the current state of surface waters in the river. The content of main ions, biogenic and inorganic ions, heavy metals, organic impurities in seasonal and annual dynamics have been studied. Results show that, despite the tightening of requirements for wastewater discharge into the Ishim River basin, a number of water quality indicators did not fulfill the regulatory requirements for surface water bodies during 2013–2019. It has been identified that the greatest pollution in the Ishim River is brought by enterprises of the Karaganda-Temirtau technogenic region, located in the upper reaches of the river. Future water quality monitoring is needed and should include increasing the number of sampling locations and the sampling frequency in order to characterize the spatial and temporal variability of hydrochemical parameters and allow a comprehensive monitoring of legally fixed water quality parameters/indicators.

The article presents the results of a survey of the operating conditions and construction of groundwater wells for the population of Shchuchinsk, Akmola region. It was established that the owners of the wells did not comply with the sanitary and hygienic requirements for the choice of a land plot for the construction of a well, the conditions for their maintenance and the creation of sanitary protection zones. The analysis of the wells' water quality made it possible to formulate a conclusion about their unsuitability for the purposes of drinking water use. It is planned to conduct further systemic studies in different seasons of the year with an increase in the sample of research objects.

With the development of chemistry, natural substances were actively supplanted from human life by chemical products. However, despite the enormous progress in this area, in recent decades, the problems of serious side effects of synthetic chemicals on the environment have become more and more pronounced. Methods of two-dimensional and one-dimensional paper chromatography, column adsorption chromatography, gas chromatography, and IR spectroscopy were used. The purpose of the article is to study the chemical composition of the Linosyris villosa plant by physicochemical methods of analysis. Creation of dosage forms based on it. The problem of the article is the search and creation of drugs based on the flora of Northern Kazakhstan. The scientific novelty lies in the fact that the chemical composition and biological activity of the Linosyris villosa plant, growing in the territory of Northern Kazakhstan, is being studied for the first time. According to the results of the analysis, in 13% of patients the treatment effect is insignificant, and in 87% of patients there was an improvement in blood values (increase in hemoglobin, an increase in the number of red blood cells, almost all patients returned color index of blood), the number of white blood cells increased to normal, and the WBC differential improved. Therefore, the drug “Vitin”, an aqueous-alcoholic extract of the Linosyris villosa, is an effective drug for the treatment of patients with anemia of varying severity. The practical significance of the work is defined as follows: biologically active compounds from the Linosyris villosa plant were obtained for the purpose of studying and applying them in medicine and agriculture.

A well-known, affordable, and cheap method of modifying biopolymers is their simple mixing with synthetic and natural polymers. As a result, similar to metal alloys, polymer-polymer complexes with predetermined properties can be obtained. Although interpolymer complexes became a subject of study and application a long time ago, in domestic practice, the study of natural biopolymers is limited. The purpose of this study was to present and study the issue of structuring in solutions of bio- and synthetic polymers, as with a low dry matter content such structures have many properties of a solid. Natural ampholytic polymers are polyelectrolytes, which is also of great importance for their further study. By analyzing the results of studies of complexes formed by a synthetic linear polyelectrolyte with a charged partner – protein, it becomes possible to create new “smart” polyelectrolyte complexes that can undergo phase changes in narrow, controlled pH ranges. The positive effect of sodium carboxymethyl cellulose on the gelation of 5% gelatine hydrogels was established. It was determined that the presence of additives of inorganic salts leads to an increase in the swelling of gelatine gels. It was established that more durable gels are less prone to aging. The practical significance of these studies is determined by the fact that in many industries (food, soap, paint, and varnish), it is necessary to obtain structures with tailor-made properties. Gel formation may also be an undesirable phenomenon that must be prevented, for example, in the production of chemical fibers, glues, and tanning solutions. Furthermore, biological objects themselves in most cases, by their nature, are protein gels with specific mechanical properties. Keywords: structure and dynamics of gelatine mixed hydrogels, adsorption on solid surfaces, collapse of heterogeneous networks, swelling and aging of mixed gelatine hydrogels.