Uma síntese limpa, fácil e eficiente de vários 1,2,4-oxadiazóis 3,5-dissubstituídos partindo de um anidrido misto (gerado a partir de um ácido carboxílico e cloroformiato de etila) e amidoxima é descrita.An efficient, clean and easy high-yielding synthesis of 3,5-disubstituted 1,2,4-oxadiazoles starting from mixed anhydrides (generated from carboxylic acids and ethyl chloroformate) and arylamidoximes is described.
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