The increasing use of nanomaterials and scalable, high-yield nanofabrication process are revolutionizing the development of novel biosensors. Over the past decades, researches on nanotechnology-mediated biosensing have been on the forefront due to their potential application in healthcare, pharmaceutical, cell diagnosis, drug delivery, and water and air quality monitoring. The advancement of nanoscale science relies on a better understanding of theory, manufacturing and fabrication practices, and the application specific methods. The topology and tunable properties of nanoparticles, a part of nanoscale science, can be changed by different manufacturing processes, which separate them from their bulk counterparts. In the recent past, different nanostructures, such as nanosphere, nanorods, nanofiber, core–shell nanoparticles, nanotubes, and thin films, have been exploited to enhance the detectability of labelled or label-free biological molecules with a high accuracy. Furthermore, these engineered-materials-associated transducing devices, e.g., optical waveguides and metasurface-based scattering media, widened the horizon of biosensors over a broad wavelength range from deep-ultraviolet to far-infrared. This review provides a comprehensive overview of the major scientific achievements in nano-biosensors based on optical fiber, nanomaterials and terahertz-domain metasurface-based refractometric, labelled and label-free nano-biosensors.

Optical sensing technologies for hydrogen monitoring are of increasing importance in connection with the development and expanded use of hydrogen and for transition to the hydrogen economy. The past decades have witnessed a rapid development of optical sensors for hydrogen monitoring due to their excellent features of being immune to electromagnetic interference, highly sensitive, and widely applicable to a broad range of applications including gas sensing at the sub-ppm range. However, the selection of hydrogen selective metal and metal alloy plays an important role. Considering the major advancements in the field of optical sensing technologies, this review aims to provide an overview of the recent progress in hydrogen monitoring. Additionally, this review highlights the sensing principles, advantages, limitations, and future development.

Recently, metasurfaces have been investigated and exploited for various applications in the THz regime, including modulators and detectors. However, the responsive properties of the metasurface in THz stay fixed once the fabrication process is complete. This limitation can be modified when integrating the phase change material (PCM), whose states are switchable between crystalline and amorphous, into the metasurface structure. This characteristic of the PCM is appealing in achieving dynamic and customizable functionality. In this work, the reflective metasurface structure is designed as a hexagonal unit deposited on a polyimide substrate. The non-volatile PCM chosen for the numerical study is germanium antimony tellurium (GST). Our proposed phase change metasurface provides two resonant frequencies located at 1.72 and 2.70 THz, respectively; one of them shows a high contrast of reflectivity at almost 80%. The effects of geometrical parameters, incident angles, and polarization modes on the properties of the proposed structure are explored. Finally, the performances of the structure are evaluated in terms of the insertion loss and extinction ratio.