Background and Aim: Promotions of goat farming by both public and private sectors encouraged considerable goat raising in central Thailand. Gastrointestinal nematodes (GIN) infection is a major health and economic problem; however, evidence of resistance to broad-spectrum anthelmintics is frequently reported. Investigation of anthelmintic resistance (AR) status and identification of factors related to the development of AR is important components for sustainable GIN control. However, no information is available on this topic in the study area. The present study aimed to gather information on GIN control practices and to evaluate the effectiveness of albendazole, ivermectin, and levamisole for treating GIN infestation in goat herds in Sing Buri Province. Materials and Methods: Twenty-nine herds were randomly selected. Information on management practices was collected by face-to-face interview using a structured questionnaire. Three field experiments for routinely used anthelmintics, including albendazole, ivermectin, and levamisole were conducted from June 2019 to November 2019. Fecal samples were collected pre- and post-treatment and examined for fecal egg count reduction to determine the status of anthelmintic resistance of goat GIN. Results: Several improper practices were identified that lead to AR, especially chronic use of albendazole and ivermectin. All herds were considered resistant to albendazole and ivermectin, and levamisole resistant nematodes were detected in two herds. AR was strongly linked with the continuous use of anthelmintics. Conclusion: Levamisole, which was still effective in the province, should be used with caution to minimize the selection of resistant strains. Farmers should be provided with updated information for sustainable parasite control. Further, the efficacy of anthelmintics should be routinely monitored.

During 2012 - 2016, goat farms in Sing Buri province were growing rapidly with support from the Thai government. In the following three years (2017-2019), the analysis of brucellosis surveillance data indicated that the seropositivity of brucellosis in goats increased. Therefore, this study attempted to identify possible risk factors associated with brucellosis seropositivity in meat goats raised in Sing Buri province of Thailand. A case-control study was conducted in a random sampling of 72 goat farms in Sing Buri province, Thailand. Questionnaires were used to collect information regarding farm production types, husbandry, goat health management, grazing management, breeding, carcass management, and goat purchasing. Bivariate and logistic regression analyses were used to determine the risk factors of Brucella seropositivity. Results revealed that the most frequent health complaint by the farmers was a stillbirth. Brucella seropositivity at the farm level was 26.4%. The two most probable risk factors for seropositivity included raising goats in a communal pasture and keeping goats with a history of clinical signs associated with brucellosis. In conclusion, approximately 25% of goat farms in Sing Buri province were infected by the bacteria genus Brucella. The farmers were recommended to attentively seek and cull for a brucellosis-suspected goat in their farms using clinical signs or symptoms together with active serosurveillance. Furthermore, communal pasture avoidance would also help prevent the goat from Brucella infection.