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Objective: The objective of the current study was evaluation of outcome of tendon transfers in high radial nerve palsy for restoration of power and function of wrist and hand in Karachi, Pakistan. Methodology: A descriptive case series with clinical data of 17 patients was analyzed at the Department of Orthopedics Surgery at the Dr. Ruth K.M. Pfau Civil Hospital at Dow University of Health Sciences in Karachi, Pakistan, from January 2018 to December 2021. Patients who were diagnosed with high and low RNP were registered. Those with multiple injuries which might have caused considerable disability (polytrauma patients) or those suffering from brachial plexus lesions were excluded. Results: Out of seventeen patients, 14 (85%) were male while 03 (15%) were femalewith mean age of 29.5 years. There were 65% right-sided injured patients. Mean of the Disabilities of the Arm, Shoulder and Hand (DASH) scores was 11.44 ± 3.35 with 94.1% patients in minimal disability category whereas 5.88% patients moderately disable.Motor power of wrist and finger extension was significantly improved between the preoperative period and three months post-operatively, between the pre-operative period and six months. Conclusion: Tendon transfers treating radial nerve palsy have positive functional outcomes in terms of wrist extension, finger extension, and handgrip strength, as well as positive patient satisfaction as measured by Quick DASH ratings. Tendon transfers help restoring nonfunctional dangling wrist and hand into functional powerful wrist and hand. Keywords: Radial nerve palsy, tendon transfers outcome, DASH scores

Objectives: The objective of our study to find the outcome of extensive chondrosarcoma pelvis after surgery. Study Design: Case Series study. Setting: Department of Orthopaedic Surgery Dow University of Health Sciences / Civil Hospital Karachi. Period: From April 2014 to December 2018. Material & Methods: Seven patients with Chondrosarcoma pelvis included in this study. Results: All Seven patients were male. 2 patient age was in 20’s, three in 40’s and two in 60’s with median age of 44. Clinically presentation of patients was variable. One patient present with groin lump, one with pain and swelling lower abdomen, three with hip pain, one patient with severe gluteal pain and lump, one with massive lump extending from the mid abdomen to groin and urine retention and constipation. Five patients have left pelvis involved and two have right side. Two patients have pubic bone and ischium (Level III) involved, two have ilium (Level I) and three have ilium, acetabulum and pubis (Level I, II, III). Two patients with have preoperatively sciatic nerve palsy. Two patients have medical comorbid. One was asthmatic and one had psychiatric illness. No patient had metastasis at presentation. Pubis and ischium with tumor resected in two cases, partial ilium resection in one case, one complete P1 resection with sciatic nerve, one patient have internal hemipelvectomy and one patient had internal hemipelvectomy that bone recycled in liquid nitrogen and pelvis re-implanted and fixed with recon plates and hip joint reconstructed with total hip replacement. One patient had external hemipelvectomy due to pus at tumor site. Total duration of surgery in patient having thirteen hours, and remaining have 3 to 5 hours. Blood loss during these surgeries was in between 1000 to 1200 ml. Three patients have wound infection, one patient had L5 nerve root injury. Patient with external hemipelvectomy develop wound dehiscence and uro-cutaneous fistula. Two patients died, one with recycled bone after 15 months due cardiac problem and 2nd due to disease related complications within 3 months of surgery. Conclusion: Pelvic chondrosarcoma must be operated by the team of surgeons including orthopaedic surgeon, urologist and general surgeon because of the tumor presents with massive lumps due to unrestricted compartment and can involve the important pelvic organ. With team any complication can be prevented and treated immediately.