Background: Progressive neurological genetic diseases are not rare. They cause psychosocial damages to its victims. This article focuses on common psychosocial issues faced by those from the developing world. Methods: A multicentre observational survey of 246 patients from teaching hospitals in Sri Lanka. Participants were clinically and genetically confirmed by neurologists and the Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience (ICIBN) respectively from 2014 to 2018. Convenience sample with random geographical distribution. Factors were equally weighted. ANOVA, Student’s t-test and chi-square analysis were used. Statistical Software R Statistics—version 3.5 and one-sample t-test with CI = 95% was used. This study meets the ethical guidelines of the local institutional review boards which are in compliance with the Helsinki Declaration. Results: Sample included 184 males and 62 females of 3–76 years with either Duchenne muscular dystrophy (n=121), spinocerebellar ataxia ( n = 87) or Huntington disease ( n = 38). Mean income of the affected is lower than the standard average monthly income ( P ≤ .001). Consultation visits depend on the monthly income (CI 20421.074–34709.361; P ≤ .001). Conclusion: Poverty is inversely proportionate to the patients’ living conditions. As developing countries are financially challenged, it is a societal challenge to rebuild our values to enhance their living status.
Solid pseudopapillary tumour (SPT) is a rare exocrine tumour of the pancreas predominately seen in females; has a 15% chance of metastasis; and represents 1-3% of all pancreatic tumours. We present two case reports of the disease: first a 13 year old female with abdominal pain and vomiting, and second a 36 year old asymptomatic female with an incidental SPT. Both patients had normal biochemical findings with well-defined masses in the pancreas in the contrast enhanced computed tomography. Treatment involved complete resection of the tumour and the latter also had a splenectomy as the tumour was adherent to the splenic vessels. Both remained asymptomatic following surgery and were followed up for a year after resection. We highlight the importance of having a high index of suspicion of the disease entity due to its varied presentation as surgical treatment provides a good prognosis.
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