Background: Cataract is among the most common ocular morbidity seen among elderly patients, it incidence is related to the aging process. It is a ocular morbidity and result in decrease the eye sight. Incidence of cataract related to aging process is generally seen in patients who are aged above 45 years of age. In previous researches it was estimated that approximately seventy five percent of general population above the 70 years of age has reported to suffer from lens opacity or cataract. Material & Methods: Patients who were presenting with nuclear or cortical or posterior sub-capsular cataracts along with healthy age and gender matched controls were enrolled from outdoor and from ward by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant. Results:  On the assessment of serum sodium levels it was found that mean serum sodium levels were 144.12 ± 2.43 meq/l in the cataract group and mean serum sodium levels were 139.37±3.4 meq/l in the age matched controls. This difference among both the groups was statistically significant (P value <0.05). On the assessment of serum potassium levels, it was found that mean serum potassium levels were 4.32 ± 0.11 meq/l in the cataract group and mean serum potassium levels were 4.10 ± 0.16 meq/l in the age matched controls. This difference among both the groups was statistically non-significant (P value >0.05). Conclusion: We concluded from the present study that the higher prevance of raised serum sodium levels in patients of senile cataract. We found that any alteration in serum electrolyte concentration leads to alterations in aqueous humor’s electrolyte concentration and responsible for risk factor for development of senile cataract. Key words: senile cataract, serum sodium, serum potassium.