Introduction: In present study an effort has been made to assess the hypoglycemic, Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model. Materials and methods: Rats were acclimatized for 7 days in lab temperature. All animals were given standard water and pellet diet. Diabetes was induced in rats with the help of alloxan monohydrate (140mg/kg body weight). After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin. Results and discussion: A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats. Antihyperglycemic, Anti-cholesterolmic and haematinic activity observed in carrot juice administered rats on 7th,14th,21st and 28th days post treatment. Anti-hyperglycemic and anti-cholesterol mic activity was found less effective than that of insulin treatment group. Conclusion: It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic, haematinic and Anti-cholesterolmic effects in experimental animal model. The results are (<0.001) statistically significant.

Starvation is experienced in most species of fish during certain periods of every year largely due to environmental conditions and it affects different organs in different ways. The present paper deals with the impact of starvation on cholesterol content of gonadal tissues of a fresh water catfish, Clarias batrachus. The level of cholesterol in the gonads has been found higher in female than in male under both the normal and starved conditions. Both the male and female gonads showed non-significant depletion up to 20 days of starvation but thereafter, it was sharp. After 40 days of starvation, the cholesterol depleted about 84% in male and 79% in female of their normal values.Our Nature (2015), 13(1): 26-30

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In this present scenario,medicinal plants are becoming popular for the treatment of various diseases all over the world. Some of them are being traditionally used in diabetes for human welfare. Diabetes is a common endocrine disorder that impairs glucose metabolism resulting in severe diabetic complications including retinopathy, angiopathy, nephropathy, neuropathy and causing neurological disorder due to perturbation in utilization of glucose. In the present study, an effort has been made to assess the antidiabetic properties of Ficus glomerata leaf extract treatment in alloxan monohydrate induced diabetic albino rats. Present study refers to the medicinal plant Ficus glomerata leaf metabolites compared to insulin treatment animal model. Diabetes was induced in albino rats with the help of alloxan monohydrate (150 mg/kg) intraperitoneal saline injection. Present study was carried out to evaluate the anti-diabetic activity of Ficus glomerata aqueous leaf extract in diabetic albino rats for 4 week treatment. The treatment with aqueous leaf extract at high dose (1g/kg) significantly decreased circulating blood glucose concentration in comparison to mild dose (500mg/kg) and low dose (100mg/kg) respectively in diabetic rats. The aqueous leaf extract also improved the hematological picture, weight, biochemical profile and glucose intolerance lowering effects in diabetic animal models. In conclusion, Ficus glomerata leaf metabolites have tremendous antidiabetic potential in alloxan-induced experimental models. The results suggest the possibility that Ficus glomerata leaves metabolites to cure diabetes in herbal medicine.

Cholesterol is an organic lipid molecule synthesized by all animal cells. It is an essential structural component of the cell membrane in all animals that is required to maintain both membrane structural integrity and fluidity. Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acids, and vitamin D. In the present investigation, the level of blood cholesterol has been estimated in both the sexes of Clariasbatrachus, which were subjected to starvation for 40 days. Cholesterol content was estimated by Sackett's Method (1925). Clariasbatrachus adapted well to starvation stress and survived all throughout the experimental period. The blood cholesterol concentration was higher in females than in males both under normal and starved conditions. After 10 days of starvation, the blood cholesterol dropped about 23 percent in male and about 21 percent in female. After30 days of starvation, more than 70 percent drop was observed in male while it was only 55 percent in female. Similarly, after 40 days of starvation the males showed more decrease (88%) than that of females(76%). The bar notation of the recorded data showed that the drop between 0 and 10, 0 and 20, 0 and 30, 0 and 40 and among 10, 20, 30and 40 days of starvation were highly significant at 1 percent of P for blood cholesterol.